Crohn's
disease and ulcerative colitis are similar. They're often mistaken
for one another. Both inflame the lining of your digestive tract.
Both can cause severe bouts of watery or bloody diarrhea and abdominal
pain. But Crohn's disease can occur anywhere in your digestive tract.
Crohn's disease often spreads deep into the layers of affected tissues.
Ulcerative colitis usually affects only the innermost lining of
your large intestine (colon) and rectum.
In
1932 the American doctor Burrill B. Crohn and his associates first
offered the description of a disease characterized by an inflammatory
reaction of the bowel, usually affecting the ileum, the colon, or
another part of the gastrointestinal tract. Crohn's disease is a
chronic, nonspecific, occurring without known cause gastrointestinal
inflammatory disease named after Burrill B. Crohn.
Crohn's
disease is sometimes referred as regional enteritis, ileitis or
ileocolitis: regional enteritis because it may be characterized
by segments of diseased bowel with sharp borders on the affected
regions; ileitis if only the ileum is involved; and ileocolitis
if both the ileum and the colon are involved.
Crohn's
disease is an inflammation upon the deeper layers of the intestinal
wall while Ulcerative colitis is a disease that causes inflammation
and sores, called ulcers, in the lining of the rectum and colon.
Ulcerative colitis and Crohn's disease cause similar symptoms that
often resemble other conditions such as irritable bowel syndrome.
The inflammation may extend to other areas of the bowel or to the
stomach, duodenum or mouth. In the advanced stages of the disease
complications may include arthritis, ankylosing spondylitis, kidney
and liver disease, and skin and eye disorders. The formation of
fistulas from the diseased bowel to the anus, vagina, skin surface,
or other loops of the bowel is common.
Crohn's
disease also can affect other parts of the body. These complications
include various forms of arthritis, kidney stones, gallstones, skin
problems, inflammation in the eyes or mouth, or other diseases of
the liver and billiary system.
Crohns
disease is characterized by frequent attacks of diarrhoea, severe
abdominal pain, nausea, fever, chills and weakness. Children with
the disease often suffer retarded physical growth.
Since
there is no known Western medical cause for Crohn's disease, there
is no specific therapy available. Drug treatment focuses on relieving
the symptoms.
There
are many theories about what causes Crohn's disease, almost all
of them have not been proven. One theory is that some agent, perhaps
a virus or a bacterium, affects the body's immune system to trigger
an inflammatory reaction in the intestinal wall. Although there
is a lot of evidence that patients with this disease have abnormalities
of the immune system, doctors do not know whether the immune problems
are a cause or a result of the disease.
Possible
risk factors for Crohn's disease include immunologic factors; infectious
agents (such as bacteria, virus or amoeba); and dietary factors
(including chemicals and drugs). Crohn's disease usually begins
before age 35, with peak incidence between 14-24 years of age. Crohns
sufferers do tend habitually to consume more sugar and less raw
fruit, vegetables and dietary fibre.
From
a Traditional Chinese Medicne point of view Crohn's disease may
be caused by constitutional deficiencies, invasion of the exterior
pathogenic factors, or unbalanced diet. Constitutional deficiencies
usually refer to spleen and kidney deficiencies. These result in
patterns of damp heat; spleen deficiency; spleen and kidney deficiencies;
and qi and blood stagnation.
Invasion
of exterior pathogenic factors refers to excessive dampness injuring
yang and the accumulation of damp-heat in the intestine. Invasion
of damp heat in the large intestine is characterized by an acute
and sudden onset of gastrointestinal symptoms. Damp heat may be
indicated by diarrhea; presence of mucous and blood in the stool;
foul-smelling stools; yellow urine; and abdominal fullness and pain.
Defecation is characterized by extreme urgency, an urgent desire
to defecate and an inability to do so, and a burning sensation of
the anus after passing the stool. As heat travels upwards, patients
may feel irritable, thirsty, and have a preference to drink cold
water. The tongue is dark red with a yellow, greasy coat; the pulse
is wiry, slippery or rapid.
Spleen
deficiency may be due to constitutional deficiency or secondary
due to excessive intake of cold and raw food. Unbalanced diet high
in raw or cold injures the spleen and stomach and obstructs their
functions in transforming and transporting food and nutrients. Patients
with chronic Crohn's disease usually have spleen deficiency that
is distinguished by a compromised ability of the spleen to transform
and transport food. The patient will have symptoms such as frequent
and severe diarrhea; watery stool with undigested food; dull abdominal
pain; poor appetite; poor digestion; and gastric discomfort after
eating. Sallow facial appearance, fatigue and lethargy are due to
chronic malabsorption and malnutrition. The tongue is pale with
a white coat; the pulse is soft and weak.
Spleen
and kidney deficiencies may be due to constitutional deficiency
or secondary due to chronic nature of the illness. One diagnostic
key of spleen and kidney deficiency is early morning diarrhea around
5:00 am. In addition, patients may have abdominal pain that increases
with cold but decreases with defecation. Patients may also have
intolerance to cold and cold extremities. The tongue is pale with
a white coat; the pulse is thready and weak.
Qi
and blood stagnation apears in an acute phase of Crohn's disease
in which the patient has severe abdominal pain and fullness with
a palpable mass in the right lower quadrant. This condition mimics
acute appendicitis. Patients may experience diarrhea, lack of appetite,
muscle wasting and lethargy. The tongue is dark purple with petechia;
the pulse is thready and knotted. |